CDK4/6 inhibitors and the cell cycle

The cell cycle - Steps a cell undergoes

to make two new daughter cells

1

G1 phase

2

S phase

3

G2 phase

4

M phase

1 Cell prepares for division.

2 Genetic material replicates.

3 Further growth in preparation for division.

4 Nuclear division, followed by cell division, creates daughter cells.

In a healthy cell the cycle is moderated, in a cancerous cell the cycle is deregulated causing cells to proliferate further

CDK4/6 inhibitor treatment prevents progression from G1 to S phase, ending cell proliferation

The cell cycle - Steps a cell undergoes

to make two new daughter cells

G1 phase

Cell prepares for division

S phase

Genetic material replicates

G2 phase

Further growth in preparation for division

M phase

Nuclear division, followed by cell division, creates daughter cells

In a healthy cell the cycle is moderated, in a cancerous cell the cycle is deregulated causing cells to proliferate further

G1 phase

S phase

G2 phase

CDK4/6 inhibitor treatment prevents progression from G1 to S phase, ending cell proliferation