How a new self-orienting ingestible device could inject drugs directly into the stomach

1

The device shape was inspired by the leopard tortoise shell, which is self-orienting

Highly curved shell enables animal to return upright if flipped over

A compressed spring

fixed in sugar glass which provides a force for the drug-loaded needle

Needle

5mm

2

The device’s low centre of mass means it can orient to a stable upright position in the stomach

 

Gravity

Centre of mass

Stomach lining

Unstable

Stable

Unstable

3

Once on the stomach lining, the device releases an injection into the issue

Sugar glass disolves activating the injection

1

The device shape was inspired by the leopard tortoise shell, which is self-orienting

Highly curved shell enables animal to return upright if flipped over

A compressed spring

fixed in sugar glass which provides a force for the drug-loaded needle

5mm

Needle

3

Once on the stomach lining, the device releases an injection into the issue

2

The device’s low centre of mass means it can orient to a stable upright position in the stomach

 

Gravity

Centre of mass

Stomach lining

Sugar glass disolves activating the injection

Unstable

Stable

Unstable