1
Doctors take biopsies of primary tumour and metastases
Tumour
2
Immune cells that have infiltrated the tumour tissue are extracted from biopsy material and grown in their billions in a lab
3
Gene sequencing of the tumour tissue reveals the main mutations that characterise it
Gene
sequence
4
The immune cells are screened to find those which target the cancer’s key mutations
Cancer
cell
Immune
cell
5
These immune cells create a powerful living drug which can adapt to cancer over the patient’s lifetime
T-cell
infusion
1
Doctors take biopsies of
primary tumour and metastases
2
Immune cells that have infiltrated the tumour tissue are extracted from biopsy material and grown in their billions in a lab
3
Gene sequencing of the tumour tissue reveals the main mutations that characterise it
Gene
sequence
Blood
drawn
Tumour
Engineered T-cells with receptors
Cancer
cell
Immune
cell
Modified
T-cell
infusion
5
These immune cells create a powerful living drug which can adapt to cancer over the patient’s lifetime
4
The immune cells are screened to find those which target the cancer’s key mutations