T-cell immunotherapy: How a patient's immune cells can kill tumours

1

Doctors take biopsies of primary tumour and metastases

Biopsy

Tumour

2

Immune cells that have infiltrated the tumour tissue are extracted from biopsy material and grown in the billions in a lab

3

Gene sequencing of the tumour tissue reveals the main mutations that characterise it

Gene sequence

4

Immune cells from tumour are screened to find those that target the cancer’s key mutations

Immune

cell

Cancerous

cell

5

These immune cells are infused back into patient where they attack and kill the cancer cells

T-cell

infusion

1

Doctors take biopsies of primary tumour and metastases

2

Immune cells that have infiltrated the tumour tissue are extracted from biopsy material and grown in the billions in a lab

3

Gene sequencing of the tumour tissue reveals the main mutations that characterise it

Biopsy

Gene sequence

Tumour

Cancerous

cell

T-cell

infusion

Immune cell

5

These immune cells are infused back into patient where they attack and kill the cancer cells

4

Immune cells from tumour are screened to find those that target the cancer’s key mutations