1
Blood is drawn from the patient and the T-cells are separated out
T-cells
normally kill
pathogen-
infected
cells
2
The T-cells are genetically engineered to produce surface receptors called Cars
Engineered
T-cell with
receptors
3
These receptors allow T-cells to recognise and attach to a specific protein on tumour cells
Cancerous
cell
4
The Car T-cells multiply in the lab while patient has chemotherapy to kill off existing T-cells
5
Transfused back into the body, the Car T-cells recognise and kill cancerous cells
Modified
T-cell
infusion
1
Blood is drawn from the patient and the T-cells are separated out
2
The T-cells are genetically engineered to produce surface receptors called Cars
3
These receptors allow T-cells to recognise and attach to a specific protein on tumour cells
Blood
drawn
T-cells normally
kill pathogen-
infected cells
Engineered T-cell
with receptors
Cancerous
cell
Modified
T-cell
infusion
Hundreds of
millions produced
5
Transfused back into the body, the Car T-cells recognise and kill cancerous cells
4
The Car T-cells multiply in the lab while patient has chemotherapy to kill off existing T-cells