How the new microbe was created

2

DNA modified

The bacterium is genetically modified with new synthetic DNA bases X

and Y

A

T

X

Y

G

C

C

Y

T

G

A

A

G

C

T

T

C

G

A

Newly created

proteins

DNA

pairs

E. coli

bug

3

Synthetic DNA base creates brand new proteins

The modified bacterium has an expanded genetic code which could be used to make proteins for medicines

Bacteria’s DNA selected

An E. coli bacterium has four natural DNA bases; A, G, C and T

2

DNA modified

The bacterium is genetically modified with new synthetic DNA bases X and Y

A

T

X

Y

G

C

C

Y

T

G

A

A

G

C

T

T

C

G

A

Newly created

proteins

DNA

pairs

E. coli

bug

3

Synthetic DNA base creates brand new proteins

The modified bacterium has an expanded genetic code which could be used to make proteins for medicines

1

Bacteria’s DNA selected

An E. coli bacterium has four natural DNA bases; A, G, C and T