How to make a three-person embryo

Parents’ nuclear material placed inside donor egg

Donor nuclear material removed and destroyed

Healthy

mitochondria

Parents’ nuclear material removed and kept

Unhealthy

mitochondria

Nucleus

3

Donor egg

2

Donor’s

fertilised egg

1

Mother’s

fertilised egg

Parents’ nuclear material placed inside donor egg

Donor nuclear material removed and destroyed

Healthy

mitochondria

Parents’ nuclear material removed and kept

Unhealthy

mitochondria

Nucleus

3

Donor egg

2

Donor’s fertilised egg

1

Mother’s fertilised egg