How modified T-cell cancer therapy works

Targeting cancer cells

Cell modification

3

2

4

1

Cancer cell

T cell

Modified cell

T cell

1

A sample of the patient's T-cells (a type of white blood cell involved in fighting infection) is taken from their blood

 

2

In the lab these cells have genetically modified sensor cells (antigen receptors) added to them that can seek out certain cancers

 

3

Modified cells are allowed to multiply

 

4

Engineered T-cells are infused back into patient where the new antigen receptors allow them to target and destroy the cancer cells

Stage 2

Targeting cancer cells

Stage 1

Cell modification

3

2

4

1

Cancer cell

T cell

Modified cell

T cell

3

Modified cells are allowed to multiply

 

4

Engineered T-cells are infused back into patient where the new antigen receptors allow them to target and destroy the cancer cells

1

A sample of the patient's T-cells (a type of white blood cell involved in fighting infection) is taken from their blood

 

2

In the lab these cells have genetically modified sensor cells (antigen receptors) added to them that can seek out certain cancers